I-70 W to Hancock, MD. At Hancock, take I-68 W to Cumberland, MD. At Cumberland, take 220 S (Greene Street Exit) through Keyser, WV until it intersects with Rt. 50 at New Creek. Stay on Rt. 50 only a short distance until it junctions with Rt 93 W. Follow Rt. 93 W to Davis. At Davis, pick up Rt. 32 S to Canaan Valley.
Follow I-66 West to I-81 South, Exit I-81 at US 48/VA55 (Exit #296) and follow west to Wardensville, WV. In Wardensville, US 48 becomes 4 lanes. Follow US 48 West until it ends. Turn left on Rt. 93 West following 93 to Davis, WV. (US 48 will be opening new sections through 2015, so stay on it until it ends!)
Take I-64 W to I-81 N. Stay on I-81 N to Harrisonburg VA. At Harrisonburg, follow Rt. 33 W to Harman, WV. At Harman, take Rt. 32 N to Canaan Valley
Take I-79 S to Morgantown, WV. From Morgantown, take I-68 E to Rt. 42 S at Friendsville, MD. Follow Rt. 42 S until it intersects with Rt. 219 S at McHenry, MD. Stay on Rt. 219 S through Oakland, MD to Thomas, WV. At Thomas, take Rt. 32 S to Canaan Valley.
Follow Rt. 33 East to Rt. 50 East out of Parkersburg, WV to Clarksburg, WV. From Clarksburg take I-79 South to Exit 99. Follow Rt. 33 East through Elkins WV to Harman, WV turning left on Rt. 32 north to Canaan Valley.
I-77 North to Beckley, WV to Rt. 19 North to I-79 North to Exit 99. Follow Rt. 33 East through Elkins WV to Harman, WV turning left on Rt. 32 north to Canaan Valley.